Source Paper
Functional assessments in the rodent stroke model
Krystal L Schaar, Miranda M Brenneman, Sean I Savitz
Experimental & Translational Stroke Medicine • 2010
View Abstract
Abstract Stroke is a common cause of permanent disability accompanied by devastating impairments for which there is a pressing need for effective treatment. Motor, sensory and cognitive deficits are common following stroke, yet treatment is limited. Along with histological measures, functional outcome in animal models has provided valuable insight to the biological basis and potential rehabilitation efforts of experimental stroke. Developing and using tests that have the ability to identify behavioral deficits is essential to expanding the development of translational therapies. The present aim of this paper is to review many of the current behavioral tests that assess functional outcome after stoke in rodent models. While there is no perfect test, there are many assessments that are sensitive to detecting the array of impairments, from global to modality specific, after stroke.
Pasta Test
Objective: Assess manual dexterity and fine motor skills in rodents through pasta handling
This is a Pasta Test protocol using Not specified in pasta test section as the model organism. The procedure involves 2 procedural steps, 1 materials. Extracted from a 2010 paper published in Experimental & Translational Stroke Medicine.
Model and subjects
Not specified in pasta test section • Not specified in pasta test section • unknown • Not specified in pasta test section • Not specified in pasta test section
Study window
~5 day study window | ~20 minutes hands-on
Core workflow
Pre-test exposure to pasta • Conduct pasta test trials
Primary readouts
- Manual dexterity
- Fine motor skills
- Forelimb function
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Pre-test exposure to pasta
Expose animals to pasta before testing to optimize performance
Note: Exposure to pasta 5 days before testing is best for optimal performance
View evidence from paper
“None (exposure to pasta 5 days before testing is best for optimal performance)”
Conduct pasta test trials
Animals perform the pasta test to assess manual dexterity and fine motor skills
Note: Conduct 3-5 trials per session
View evidence from paper
“Pasta Test None (exposure to pasta 5 days before testing is best for optimal performance) 3-5 trials 10-20”