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A programmable protocol library. Open-access papers in, reproducible protocols out. Built by ConductScience.

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replicatescience.com / protocols / evidence-backed methods

323 method pages - quoted from open-access papers

Methods are not
recipes. Make
them reproducible.

ReplicateScience turns dense methods sections from open-access papers into structured, step-by-step protocols, with every fact quoted from the paper. We are rebuilding each page from the full paper; until then a page shows only the paper's own words.

PopularMorris water mazeFear extinctionOptogeneticsELISAPatch-clampWhisker discrimination
Browse all experiments API (in development)
Open-access onlyQuoted from the paperNo paywalls
Recently published
view all ->
Plant growth improvement mediated by nitrate capture in co-composted biochar methods3 quoted passagesDraftExperimental adaptation of an influenza H5 haemagglutinin (HA) confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets methods3 quoted passagesDraftRegulation of prefrontal cortex myelination by the microbiota methods3 quoted passagesDraft
Method pages
323
being rebuilt
Papers
322
open-access
Scientists
113
credited
Institutions
86
indexed
Evidence quotes
2,158
sourced
The pipeline

How a paper becomes a protocol.

We are rebuilding every page through these four stages. Each fact must match the paper's own words, or it is not shown.

Stage 01

Ingest

Open-access papers from PubMed Central, bioRxiv, and medRxiv are segmented into structured method text.

PDF/XMLstructured text
Stage 02

Extract

Each experiment is read into steps, settings, materials, and subjects, with the exact quote for every fact.

methodsprotocol json
Stage 03

Match

Equipment is linked to a catalog item only when the paper names its maker or model.

equipment
Recent

Fresh from the lab.

Browse all protocols
source-backed-method-packageDraft

Plant growth improvement mediated by nitrate capture in co-composted biochar methods

Plant growth improvement mediated by nitrate capture in co-composted biochar

claudia i kammann3 quoted passages
source-backed-method-packageDraft

Experimental adaptation of an influenza H5 haemagglutinin (HA) confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets methods

Experimental adaptation of an influenza H5 haemagglutinin (HA) confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

masaki imai
One library, two surfaces

For the bench, and for the IDE.

Run an assay tomorrow morning, or pipe protocols into a meta-analysis. The site and the API will serve the same checked records; the API is in development.

Bench scientists

Methods with their sources, quoted from the paper, in print-friendly form.

PIs and reviewers

Every fact carries the paper's exact words, so you can check it at a glance.

Developers and data teams

A REST API and Python package for structured protocol records, in development.

pythoncurl
Principles

Four commitments we make to anyone reading a protocol here.

01

Evidence before claim

Every step, parameter, and equipment match links back to a source methods quote.

02

Open access only

We process open-access literature, attribute sources, and do not scrape paywalls.

03

Confidence over completeness

Scores expose missing details rather than filling gaps with plausible fiction.

04

Machine-readable by default

The web interface and API use the same structured protocol records.

Get started

Find a protocol.
Or ship one.

Open access. Always free to read. Submit any open-access paper for extraction and review.

Browse protocols Submit a paper
API

The API and Python package are in development. They will serve the same checked records as the method pages.

Developer notes
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease methods4 quoted passages
Draft
Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density methods5 quoted passagesDraft
Re-epithelialization and immune cell behaviour in an ex vivo human skin model methods4 quoted passagesDraft
linked SKUs
Stage 04

Review

A trained reviewer checks each fact against the paper before it counts.

draftchecked
3 quoted passages
source-backed-method-packageDraft

Regulation of prefrontal cortex myelination by the microbiota methods

Regulation of prefrontal cortex myelination by the microbiota

a e hoban3 quoted passages
source-backed-method-packageDraft

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease methods

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

patricia spilman4 quoted passages
source-backed-method-packageDraft

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density methods

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

kellie s gross5 quoted passages
source-backed-method-packageDraft

Re-epithelialization and immune cell behaviour in an ex vivo human skin model methods

Re-epithelialization and immune cell behaviour in an ex vivo human skin model

ana rakita4 quoted passages
typescript
api/v1
# pip install replicatescience
from replicatescience import ReplicateScience

rs = ReplicateScience(api_key="rs_live_...")

# Search the methods literature
protocols = rs.protocols.search(
  species="Mus musculus",
  type="fear_conditioning",
  min_completeness=85,
)

# Each protocol carries evidence
for p in protocols:
  print(p.title, p.completeness)
  for step in p.steps:
    print(step.evidence)
Same data the browse pages renderin development