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ReplicateScience

A programmable protocol library. Open-access papers in, reproducible protocols out. Built by ConductScience.

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replicatescience.com / protocols / evidence-backed methods

323 protocols - evidence-backed methods

Methods are not
recipes. Make
them reproducible.

ReplicateScience turns dense methods sections from open-access papers into structured, step-by-step protocols with equipment mappings, evidence quotes, and an API any biologist can call.

PopularMorris water mazeFear extinctionOptogeneticsELISAPatch-clampWhisker discrimination
Browse all experiments Use the API
Open-access onlyEvery claim has evidenceNo paywalls, no scraping
Recently published
view all ->
2h agoPlant growth improvement mediated by nitrate capture in co-composted biochar methodshuman - 3 steps - 3 quotes90/1006h agoExperimental adaptation of an influenza H5 haemagglutinin (HA) confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets methodsmouse - 3 steps - 3 quotes
Protocols
323
approved
Papers
322
open-access
Scientists
113
credited
Institutions
86
indexed
Evidence quotes
2,158
sourced
API surface
v1
REST ready
The pipeline

How a paper becomes a protocol.

Four deterministic stages. Every output traces back to the original Methods section. Nothing is invented.

Stage 01

Ingest

Open-access papers from PubMed Central, bioRxiv, and medRxiv are segmented into structured method text.

PDF/XMLstructured text
Stage 02

Extract

Each distinct experiment is parsed into atomic steps, parameters, materials, subjects, and evidence quotes.

methodsprotocol json
Stage 03

Match

Equipment mentions are confidence-matched against catalog records and never invented.

equipment
Recent

Fresh from the lab.

Browse all protocols
source-backed-method-package90/100

Plant growth improvement mediated by nitrate capture in co-composted biochar methods

human

Plant growth improvement mediated by nitrate capture in co-composted biochar

claudia i kammann3 steps - 3 eq.
source-backed-method-package
One library, two surfaces

For the bench, and for the IDE.

Run an assay tomorrow morning, or pipe a thousand protocols into a meta-analysis tonight. The browsable site and API are the same evidence-backed data.

Bench scientists

Browsable protocols with prices, sources, and print-friendly execution details.

PIs and reviewers

Completeness scores and evidence quotes make reproducibility auditable at a glance.

Developers and data teams

REST API, API keys, OpenAPI-compatible responses, and structured protocol JSON.

pythoncurl
Principles

Four commitments we make to anyone reading a protocol here.

01

Evidence before claim

Every step, parameter, and equipment match links back to a source methods quote.

02

Open access only

We process open-access literature, attribute sources, and do not scrape paywalls.

03

Confidence over completeness

Scores expose missing details rather than filling gaps with plausible fiction.

04

Machine-readable by default

The web interface and API use the same structured protocol records.

Get started

Find a protocol.
Or ship one.

Open access. Always free to read. Submit any open-access paper for extraction and review.

Browse protocols Submit a paper
API tiers
Free100 req/dayno card
Pro5,000 req/day$29/mo
Institutional50,000 req/daycontact
See API docs
90/100
1d agoRegulation of prefrontal cortex myelination by the microbiota methodsmouse - 3 steps - 3 quotes90/100
2d agoInhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease methodsmouse - 4 steps - 4 quotes95/100
3d agoOpposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density methodsrat - 5 steps - 5 quotes95/100
5d agoRe-epithelialization and immune cell behaviour in an ex vivo human skin model methodshuman - 4 steps - 4 quotes90/100
linked SKUs
Stage 04

Review

A reviewer verifies steps, evidence, and product mappings before indexing.

draftapproved
90/100

Experimental adaptation of an influenza H5 haemagglutinin (HA) confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets methods

mouse

Experimental adaptation of an influenza H5 haemagglutinin (HA) confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

masaki imai3 steps - 3 eq.
source-backed-method-package90/100

Regulation of prefrontal cortex myelination by the microbiota methods

mouse

Regulation of prefrontal cortex myelination by the microbiota

a e hoban3 steps - 4 eq.
source-backed-method-package95/100

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease methods

mouse

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

patricia spilman4 steps - 3 eq.
source-backed-method-package95/100

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density methods

rat

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

kellie s gross5 steps - 3 eq.
source-backed-method-package90/100

Re-epithelialization and immune cell behaviour in an ex vivo human skin model methods

human

Re-epithelialization and immune cell behaviour in an ex vivo human skin model

ana rakita4 steps - 2 eq.
typescript
api/v1
# pip install replicatescience
from replicatescience import ReplicateScience

rs = ReplicateScience(api_key="rs_live_...")

# Search the methods literature
protocols = rs.protocols.search(
  species="Mus musculus",
  type="fear_conditioning",
  min_completeness=85,
)

# Each protocol carries evidence
for p in protocols:
  print(p.title, p.completeness)
  for step in p.steps:
    print(step.evidence)
Same data the browse pages render200 OK - 84ms