Source Paper
Prefrontal Glutamate Release into the Core of the Nucleus Accumbens Mediates Cocaine-Induced Reinstatement of Drug-Seeking Behavior
Krista McFarland, Christopher C. Lapish, Peter W. Kalivas
Journal of Neuroscience • 2003
Cocaine-Primed Reinstatement Test
Objective: To assess the relative contributions of glutamate and dopamine within the nucleus accumbens to cocaine-induced reinstatement of drug-seeking behavior by measuring extracellular neurotransmitter levels when extinguished cocaine self-administration behavior is reinstated by a cocaine-priming injection
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Equipment3
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Materials2
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