Conditioned Place Preference Test
Objective: Assessment of rewarding effects of URB597 using conditioned place preference paradigm to determine if the compound produces rewarding effects comparable to direct CB1 agonists
This is a Conditioned Place Preference Test protocol using Not explicitly stated in provided text as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2005 paper published in Proceedings of the National Academy of Sciences.
Model and subjects
Not explicitly stated in provided text • Not explicitly stated in provided text • unknown • Not explicitly stated in provided text • Not explicitly stated in provided text
Study window
Estimated timing pending
Core workflow
Conditioned Place Preference Test
Primary readouts
- Presence or absence of rewarding effects of URB597
- Comparison of rewarding properties between URB597 and direct CB1 agonists
- Generalization to discriminative effects of Δ9-tetrahydrocannabinol
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Conditioned Place Preference Test
Assessment of rewarding effects of URB597 using conditioned place preference paradigm. The test measures whether animals develop preference for environments paired with drug administration.
Note: Unlike direct CB1 agonists, URB597 does not exert rewarding effects in this test
View evidence from paper
“URB597 does not exert rewarding effects in the conditioned place preference test or produce generalization to the discriminative effects of Δ9-tetrahydrocannabinol in rats”