Conditioned Place Preference Test
Objective: Assessment of rewarding effects of URB597 using conditioned place preference paradigm to determine if the compound produces rewarding effects comparable to direct CB1 agonists
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Equipment1
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Protocol Steps
Conditioned Place Preference Test
Assessment of rewarding effects of URB597 using conditioned place preference paradigm. The test measures whether animals develop preference for environments paired with drug administration.
Note: Unlike direct CB1 agonists, URB597 does not exert rewarding effects in this test
View evidence from paper
“URB597 does not exert rewarding effects in the conditioned place preference test or produce generalization to the discriminative effects of Δ9-tetrahydrocannabinol in rats”