Source Paper
Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress
D. L. Champagne, R. C. Bagot, F. van Hasselt, G. Ramakers, M. J. Meaney et al.
Journal of Neuroscience • 2008
Contextual Fear Conditioning
Objective: Hippocampal-dependent behavioral test measuring memory formation and retention in offspring exposed to contextual fear conditioning, examining effects of maternal licking and grooming on cognitive performance
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Protocol Steps
Contextual Fear Conditioning Test
Adult offspring were tested in a hippocampal-dependent contextual fear-conditioning paradigm to measure memory formation and retention
Note: Test was conducted on adult offspring from mothers with varying frequencies of licking and grooming behavior
View evidence from paper
“Adult low LG offspring displayed enhanced memory relative to high LG offspring when tested in a hippocampal-dependent, contextual fear-conditioning paradigm”