Source Paper
Tubuloside B ameliorates blood-brain barrier disruption and cognitive deficits after cerebral ischemia by inhibiting TRIC protein ubiquitination and degradation
He M, Zhang H, Liu R, Zhang C, Li J et al.
J Neuroinflammation • 2025
Morris Water Maze
behavioralRatSprague-Dawley
Objective: To assess spatial learning and memory abilities using a water maze behavioral test
Materials & Equipment Checklist
1 item1 from ConductScience
Gather these items before starting the experiment. Check off items as you prepare.
Materials1
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Protocol Steps
1
Training phase
Conduct spatial learning training over 5 consecutive days with hidden platform
View evidence from paper
“Spatial learning and memory were assessed over 5 training days with a hidden platform”
2
Probe test
Perform probe test on day 6 following training
View evidence from paper
“A probe test was conducted on day 6”
3
Data recording
Record escape latency, path length, and time spent in target quadrant
View evidence from paper
“Escape latency, path length, and time in the target quadrant were recorded”
4
Blinded analysis
Perform behavioral tests and data analysis by blinded investigators
View evidence from paper
“Behavioral tests and data analysis were performed by investigators blinded to the group assignments”