Source Paper
Bilateral Orbital Prefrontal Cortex Lesions in Rhesus Monkeys Disrupt Choices Guided by Both Reward Value and Reward Contingency
Alicia Izquierdo, Robin K. Suda, Elisabeth A. Murray
Journal of Neuroscience • 2004
Object Discrimination Learning
Objective: To assess monkeys' acquisition of object discrimination learning problems and evaluate basic discriminatory ability in control and lesioned animals
This is a Object Discrimination Learning protocol using rhesus monkey as the model organism. The procedure involves 2 procedural steps, 1 materials. Extracted from a 2004 paper published in Journal of Neuroscience.
Model and subjects
rhesus monkey • 10
Study window
Estimated timing pending
Core workflow
Object Discrimination Learning Acquisition • Performance Comparison
Primary readouts
- Acquisition of object discrimination learning problems
- Ability to discriminate between objects
- Performance comparison between lesioned and control monkeys
Key equipment and reagents
Verified items
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Direct vendor links
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Protocol Steps
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Object Discrimination Learning Acquisition
Monkeys were tested on acquisition of object discrimination learning problems to assess their basic discriminatory ability
Note: This test was used to compare performance between lesioned and control monkeys
View evidence from paper
“The same monkeys, however, were unimpaired in acquisition of object discrimination learning problems”
Performance Comparison
Responses of monkeys with bilateral PFo removals were compared to unoperated control monkeys on object discrimination learning acquisition
Note: Lesioned monkeys showed no impairment on this task relative to controls
View evidence from paper
“we compared four rhesus monkeys with two-stage bilateral PFo removals and six unoperated controls”