Source Paper
Functional assessments in the rodent stroke model
Krystal L Schaar, Miranda M Brenneman, Sean I Savitz
Experimental & Translational Stroke Medicine • 2010
View Abstract
Abstract Stroke is a common cause of permanent disability accompanied by devastating impairments for which there is a pressing need for effective treatment. Motor, sensory and cognitive deficits are common following stroke, yet treatment is limited. Along with histological measures, functional outcome in animal models has provided valuable insight to the biological basis and potential rehabilitation efforts of experimental stroke. Developing and using tests that have the ability to identify behavioral deficits is essential to expanding the development of translational therapies. The present aim of this paper is to review many of the current behavioral tests that assess functional outcome after stoke in rodent models. While there is no perfect test, there are many assessments that are sensitive to detecting the array of impairments, from global to modality specific, after stroke.
Radial Arm Maze
Objective: Assessment of spatial learning and memory using a multi-armed radial maze
This is a Radial Arm Maze protocol using Not specified in text as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2010 paper published in Experimental & Translational Stroke Medicine.
Model and subjects
Not specified in text • Not specified in text • unknown • Not specified in text • Not specified in text
Study window
Estimated timing pending
Core workflow
Radial Arm Maze Testing
Primary readouts
- Spatial learning performance
- Memory retention
- Task completion metrics
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Radial Arm Maze Testing
Animals are tested in the radial arm maze to assess spatial learning and memory capabilities
Note: Training time, number of trials per session, and time to complete test are all dependent upon the specific task parameters, which are not detailed in this review text
View evidence from paper
“Radial Arm Maze Dependent upon task Dependent upon task Dependent upon task”