Source Paper
Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation
James A. Joseph, Barbara Shukitt-Hale, Natalia A. Denisova, Donna Bielinski, Antonio Martin et al.
Journal of Neuroscience • 1999
Accelerod Task
Objective: Measurement of motor performance on an accelerating rotarod to assess balance and motor coordination in aged rats
This is a Accelerod Task protocol using rat as the model organism. The procedure involves 2 procedural steps, 1 equipment items, 3 materials. Extracted from a 1999 paper published in Journal of Neuroscience.
Model and subjects
rat • Fischer 344 • not specified • 19 months old • not specified • not specified
Study window
~8 week study window
Core workflow
Dietary supplementation period • Accelerod task performance assessment
Primary readouts
- Motor behavioral performance on accelerod task
- Balance and motor coordination
Key equipment and reagents
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Protocol Steps
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Dietary supplementation period
Administer dietary supplements to 19-month-old Fischer 344 rats for 8 weeks prior to behavioral testing
Note: Three treatment groups: strawberry (14.8 gm/kg diet), spinach (9.1 gm/kg diet), or blueberry (18.6 gm/kg diet) extracts
View evidence from paper
“such supplements (strawberry, spinach, or blueberry at 14.8, 9.1, or 18.6 gm of dried aqueous extract per kilogram of diet, respectively) fed for 8 weeks to 19-month-old Fischer 344 rats”
Accelerod task performance assessment
Place rats on the accelerating rotarod and measure motor performance, balance, and motor coordination
Note: Task assesses motor behavioral performance
View evidence from paper
“motor behavioral performance on the rod walking and accelerod tasks”