Source Paper
Time-Dependent Increases in Brain-Derived Neurotrophic Factor Protein Levels within the Mesolimbic Dopamine System after Withdrawal from Cocaine: Implications for Incubation of Cocaine Craving
Jeffrey W. Grimm, Lin Lu, Teruo Hayashi, Bruce T. Hope, Tsung-Ping Su et al.
Journal of Neuroscience • 2003
Extinction Testing
Objective: To assess resistance to extinction by measuring lever presses during a 6-hour period when presses are not reinforced and the cue is absent
Gather these items before starting the experiment. Check off items as you prepare.
Equipment2
Materials2
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Protocol Steps
Extinction Testing
Assess resistance to extinction by measuring lever presses during a 6-hour period in which lever presses are not reinforced and the cue is absent
Note: This test measures how long rats continue to press the lever despite lack of reinforcement and absence of the previously paired cue
View evidence from paper
“resistance to extinction was assessed during 6 hr in which lever presses were not reinforced and the cue was absent”