An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction

Shelly B Flagel, Terry E Robinson, Jeremy J Clark, Sarah M Clinton, Stanley J Watson et al.

Neuropsychopharmacology • 2009

DOI PMC

Impulsive Choice Task

behavioralratBred high-responder (bHR) and bred low-responder (bLR) lines

Objective: Characterize impulsive choice behavior in bred high-responder (bHR) and bred low-responder (bLR) rats to assess genetic vulnerability to behavioral disinhibition and addiction-related traits

This is a Impulsive Choice Task protocol using rat as the model organism. The procedure involves 1 procedural steps. Extracted from a 2009 paper published in Neuropsychopharmacology.

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Replication Essentials

Model and subjects

rat • Bred high-responder (bHR) and bred low-responder (bLR) lines • unknown • Not specified • Not specified

Study window

Estimated timing pending

Core workflow

Impulsive Choice Task Assessment

Primary readouts

Impulsive choice behavior (preference for immediate vs delayed rewards)
Impulsive action (difficulty withholding action to receive reward)
Behavioral disinhibition
Cue approach behavior (sign tracking vs goal tracking)

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