Mechanical Allodynia Testing
Objective: Assessment of mechanical sensitivity and allodynia in hind paws following spinal cord injury in rats receiving Schwann cell transplants
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Protocol Steps
Mechanical allodynia assessment
Mechanical sensitivity testing was performed on hind paws to assess allodynia following spinal cord injury and transplantation
Note: Testing was conducted as part of comprehensive sensory function evaluation alongside thermal sensitivity testing
View evidence from paper
“examined the effects of these modifications on graft volume, SC number, degradation of chondroitin sulfate proteoglycans (CSPGs), astrogliosis, SC myelination of axons, propriospinal and supraspinal axon numbers, locomotor outcome (BBB scoring, CatWalk gait analysis), and mechanical and thermal sensitivity on the hind paws”
Thermal sensitivity assessment
Thermal sensitivity testing was performed on hind paws to assess thermal allodynia
Note: Conducted in conjunction with mechanical allodynia testing
View evidence from paper
“mechanical and thermal sensitivity on the hind paws”