Morris Water Maze
Objective: Assess spatial learning and memory performance in rats using the Morris water maze task
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Materials1
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Protocol Steps
Administer CRF1 antagonist
Administer CRF1 receptor blocker either centrally or peripherally following the early-life stress period
Note: Treatment timing is post-stress period
View evidence from paper
“Central or peripheral administration of a CRF1 blocker following the stress period improved memory performance”
Conduct Morris water maze testing
Test spatial learning and memory performance in the Morris water maze apparatus
Note: Performed on middle-aged rats with early-life stress history
View evidence from paper
“memory performance of CES rats in novel-object recognition tests and in the Morris water maze”