Novel-Object Recognition Test
Objective: Assess recognition memory and cognitive function by measuring animals' ability to discriminate between familiar and novel objects
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2 items available from ConductScience
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Protocol Steps
Animal exposure to novel objects
Animals are exposed to novel objects in the testing apparatus to assess their recognition memory and ability to discriminate between familiar and novel stimuli
Note: Testing was conducted on middle-aged early-life stressed (CES) rats and control animals
View evidence from paper
“improved memory performance of CES rats in novel-object recognition tests”
CRF1 receptor antagonist administration
Central or peripheral administration of a CRF1 blocker following the stress period to test effects on memory performance
Note: Administration was post-hoc, following the initial stress period
View evidence from paper
“Central or peripheral administration of a CRF1 blocker following the stress period improved memory performance of CES rats”
Memory performance assessment
Evaluation of recognition memory performance in novel-object recognition tests following CRF1 antagonist treatment
Note: Performance was compared between treated and untreated animals
View evidence from paper
“Central or peripheral administration of a CRF1 blocker following the stress period improved memory performance of CES rats in novel-object recognition tests”