Porsolt Forced Swim Test
Objective: Assessment of antidepressant-like effects through measurement of immobility in rats subjected to forced swimming
This is a Porsolt Forced Swim Test protocol using rat as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2012 paper published in Neuropsychopharmacology.
Model and subjects
rat • Not specified • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Porsolt Forced Swim Test
Primary readouts
- Immobility duration during forced swimming
- Antidepressant-like effects
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Porsolt Forced Swim Test
Rats are subjected to forced swimming to assess antidepressant-like effects. The test measures immobility as an indicator of depressive-like behavior.
Note: This test was used to evaluate the antidepressant-like effects of GLYX-13 in comparison to ketamine
View evidence from paper
“produces an antidepressant-like effect in the Porsolt, novelty induced hypophagia, and learned helplessness tests in rats”