Pre-pulse Inhibition Test
Objective: Measurement of sensorimotor gating to evaluate dissociative side effects of GLYX-13
This is a Pre-pulse Inhibition Test protocol using rat as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2012 paper published in Neuropsychopharmacology.
Model and subjects
rat • not specified • unknown • not specified • not specified
Study window
Estimated timing pending
Core workflow
Pre-pulse Inhibition Test
Primary readouts
- Sensorimotor gating response
- Presence or absence of dissociative side effects
- Comparison of GLYX-13 effects to ketamine effects on gating
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Pre-pulse Inhibition Test
Conduct pre-pulse inhibition test to measure sensorimotor gating as an indicator of dissociative side effects
Note: Test was used to evaluate whether GLYX-13 exhibits dissociative side effects similar to ketamine
View evidence from paper
“pre-pulse inhibition and open-field tests”