Reacquisition Test
Objective: To test whether amphetamine-sensitized rats had acquired an aversion to a devalued reinforcer by examining reacquisition of lever pressing behavior
This is a Reacquisition Test protocol using rat as the model organism. The procedure involves 5 procedural steps, 1 equipment items, 2 materials. Extracted from a 2006 paper published in Journal of Neuroscience.
Model and subjects
rat • Not specified • unknown • Not specified • Not specified
Study window
~1 week study window
Core workflow
Sensitization treatment (Experiment 1) • Lever press training • Outcome devaluation
Primary readouts
- Lever pressing behavior during reacquisition
- Evidence of aversion to devalued reinforcer
- Comparison of responding between control and amphetamine-sensitized animals
Key equipment and reagents
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Protocol Steps
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Sensitization treatment (Experiment 1)
Animals received amphetamine sensitization for 7 days at 2 mg/kg/d before training began
Note: This was the pre-training sensitization condition in experiment 1
View evidence from paper
“Animals were either sensitized (7 d, 2 mg/kg/d) before training (experiment 1)”
Lever press training
Rats were trained to press a lever to obtain a reward
Note: Training occurred after sensitization in experiment 1
View evidence from paper
“Rats were trained to press a lever for a reward (three sessions)”
Outcome devaluation
The instrumental outcome (reward) was devalued to test goal sensitivity
Note: This test occurred before extinction testing to assess whether behavior remained goal-directed
View evidence from paper
“were then given a test of goal sensitivity by devaluation of the instrumental outcome before testing in extinction”
Extinction test
Animals were tested in extinction following outcome devaluation
Note: Performance in extinction was measured to assess sensitivity to devaluation
View evidence from paper
“before testing in extinction”
Reacquisition test
Animals were tested for reacquisition of lever pressing to confirm they had acquired an aversion to the devalued reinforcer
Note: This test confirmed that all animals had acquired an aversion to the reinforcer despite showing persistent responding in extinction
View evidence from paper
“a reacquisition test confirmed that all of the animals had acquired an aversion to the reinforcer”