Source Paper
Neurotoxic Lesions of Basolateral, But Not Central, Amygdala Interfere with Pavlovian Second-Order Conditioning and Reinforcer Devaluation Effects
Tammy Hatfield, Jung-Soo Han, Michael Conley, Michela Gallagher, Peter Holland
Journal of Neuroscience • 1996
Reinforcer Devaluation
Objective: To assess whether rats can adjust their conditioned responses to current reinforcer value after postconditioning changes in reinforcer value, testing the role of basolateral amygdala in reinforcer devaluation effects
This is a Reinforcer Devaluation protocol using rat as the model organism. The procedure involves 3 procedural steps. Extracted from a 1996 paper published in Journal of Neuroscience.
Model and subjects
rat • Not specified • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Initial Pavlovian Conditioning • Reinforcer Devaluation Test • Measurement of Conditioned Response Adjustment
Primary readouts
- Conditioned response (CR) magnitude or frequency
- Sensitivity of conditioned responding to postconditioning changes in reinforcer value
- Ability to spontaneously adjust CRs to current reinforcer value
Key equipment and reagents
Verified items
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Direct vendor links
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Protocol Steps
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Initial Pavlovian Conditioning
Rats first received light-food pairings intended to endow the light with reinforcing power through classical conditioning
Note: This establishes the light as a conditioned stimulus with positive incentive value
View evidence from paper
“rats first received light–food pairings intended to endow the light with reinforcing power”
Reinforcer Devaluation Test
Conditioned responding was tested after postconditioning changes in reinforcer value to assess whether rats could adjust their conditioned responses to current reinforcer value
Note: This procedure measures whether the conditioned response (CR) is sensitive to changes in the value of the reinforcer
View evidence from paper
“Conditioned responding was tested after postconditioning changes in reinforcer value to assess whether rats could adjust their conditioned responses to current reinforcer value”
Measurement of Conditioned Response Adjustment
Rats with CN lesions, like normal rats, were able to spontaneously adjust their CRs to the current value of the reinforcer, whereas rats with ABL lesions showed insensitive conditioned responding
Note: The key outcome measure is whether conditioned responding adjusts based on current reinforcer value
View evidence from paper
“rats with CN lesions, like normal rats, were able to spontaneously adjust their CRs to the current value of the reinforcer”