Temporal Order Memory Task
Objective: Assess recency discrimination and memory for the temporal sequence of stimuli to evaluate the role of medial prefrontal cortex and perirhinal cortex in temporal order recognition memory
This is a Temporal Order Memory Task protocol using rat as the model organism. The procedure involves 2 procedural steps. Extracted from a 2007 paper published in Journal of Neuroscience.
Model and subjects
rat • DA rats • male • Not specified • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Surgical lesion placement • Temporal order memory task
Primary readouts
- Performance on temporal order memory task (recency discrimination)
- Performance on object-in-place task (associational memory)
- Performance on novel object preference task (familiarity discrimination)
- Performance on object location task
Key equipment and reagents
Verified items
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Direct vendor links
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Protocol Steps
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Surgical lesion placement
Male DA rats received bilateral lesions in the perirhinal cortex (PRH) or medial prefrontal cortex (mPFC), or unilateral lesions placed in both cortices in either the same hemisphere (PRH-mPFC IPSI) or contralateral hemispheres (PRH-mPFC CONTRA). A control group underwent sham surgery.
Note: Five experimental groups total including sham control
View evidence from paper
“Male DA rats received bilateral lesions in the PRH or mPFC or unilateral lesions placed in both cortices in either the same (PRH–mPFC IPSI) or contralateral (PRH–mPFC CONTRA) hemispheres. A fifth group underwent sham surgery (SHAM).”
Temporal order memory task
Rats were tested on a temporal order memory task to assess recency discrimination and memory for the temporal sequence of stimuli. This task was one of a series of behavioral tests including novel object preference task, object-in-place task, and object location task.
Note: Part of a series of recognition memory tests examining different aspects of memory
View evidence from paper
“a series of behavioral tests: a novel object preference task, an object-in-place task, and a temporal order memory task”