Source Paper
Mateus M Bergamaschi, Regina Helena Costa Queiroz, Marcos Hortes Nisihara Chagas, Danielle Chaves Gomes de Oliveira, Bruno Spinosa De Martinis et al.
Neuropsychopharmacology • 2011
Objective: Measure subjective mood parameters including anxiety, cognitive impairment, discomfort, and alertness at multiple time points during a simulated public speaking test using the Visual Analogue Mood Scale (VAMS)
Gather these items before starting the experiment. Check off items as you prepare.
Not specified • Not mentioned
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Allocate 24 treatment-naïve SAD patients to receive either CBD (600 mg, n=12) or placebo (n=12) in a double-blind randomized design. Include 12 healthy control subjects who perform SPST without medication.
Note: Double-blind procedure; each volunteer participated in only one experimental session
“A total of 24 never-treated patients with SAD were allocated to receive either CBD (600 mg; n=12) or placebo (placebo; n=12) in a double-blind randomized design”
Administer CBD (600 mg) or placebo to SAD patients 1 hour and 30 minutes before the simulated public speaking test
Note: Double-blind administration
“CBD (600 mg; n=12) or placebo (placebo; n=12) in a double-blind randomized design 1 h and a half before the test”
Administer Visual Analogue Mood Scale (VAMS) at baseline (first of six time points) to measure subjective mood parameters including anxiety, cognitive impairment, discomfort, and alertness
Note: First measurement time point
“Subjective ratings on the Visual Analogue Mood Scale (VAMS) and Negative Self-Statement scale (SSPS-N) and physiological measures (blood pressure, heart rate, and skin conductance) were measured at six different time points during the SPST”
Measure physiological parameters including blood pressure, heart rate, and skin conductance at baseline (first of six time points)
Note: First measurement time point
“physiological measures (blood pressure, heart rate, and skin conductance) were measured at six different time points during the SPST”
Subjects perform the simulated public speaking test (SPST) while mood and physiological measures are collected at five additional time points throughout the test
Note: Measurements taken at six total time points during SPST
“Subjective ratings on the Visual Analogue Mood Scale (VAMS) and Negative Self-Statement scale (SSPS-N) and physiological measures (blood pressure, heart rate, and skin conductance) were measured at six different time points during the SPST”
Administer Visual Analogue Mood Scale at five additional time points during and after the SPST to assess changes in anxiety, cognitive impairment, discomfort, and alertness
Note: Repeated measurement throughout SPST
“Subjective ratings on the Visual Analogue Mood Scale (VAMS) were measured at six different time points during the SPST”
Measure blood pressure, heart rate, and skin conductance at five additional time points during and after the SPST
Note: Repeated measurement throughout SPST
“physiological measures (blood pressure, heart rate, and skin conductance) were measured at six different time points during the SPST”
Administer Negative Self-Statement scale (SSPS-N) at six different time points during the SPST to measure negative self-statements
Note: Repeated measurement throughout SPST
“Subjective ratings on the Visual Analogue Mood Scale (VAMS) and Negative Self-Statement scale (SSPS-N) were measured at six different time points during the SPST”
24 treatment-naïve patients with Generalized Social Anxiety Disorder (SAD) allocated to CBD (n=12) or placebo (n=12); 12 healthy control subjects performed SPST without medication