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replicatescience.com / protocols / evidence-backed methods

Protocol index

Browse reproducible experimental methods.

Step-by-step protocols from open-access papers, prioritized for methods evidence, equipment mapping, and canonical ConductGraph sync.

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323 experiments found

source-backed-method-package90/100

Mitochondrial protective effects of ellagic acid in a rat model of sporadic Alzheimer's disease induced by STZ methods

forouzan khodaei

Mitochondrial protective effects of ellagic acid in a rat model of sporadic Alzheimer's disease induced by STZ

ratMethods-Backed
20260 equipment8 steps
PreviousPage 10 of 27Next
8 quotes
source-backed-method-package95/100

Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2 methods

jessica a cardin

Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2

Methods-Backed
20100 equipment8 steps8 quotes
source-backed-method-package90/100

Lipopolysaccharide regulation of intestinal tight junction permeability is mediated by TLR-4 signal transduction pathway activation of FAK and MyD88 methods

shuhong guo

Lipopolysaccharide regulation of intestinal tight junction permeability is mediated by TLR-4 signal transduction pathway activation of FAK and MyD88

mouseMethods-Backed
20150 equipment8 steps8 quotes
source-backed-method-package90/100

Acute inflammatory profiles differ with sex and age after spinal cord injury methods

andrew n stewart

Acute inflammatory profiles differ with sex and age after spinal cord injury

mouseMethods-Backed
20210 equipment7 steps7 quotes
source-backed-method-package90/100

Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis methods

d taliaz

Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis

ratMethods-Backed
20090 equipment8 steps8 quotes
source-backed-method-package90/100

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity methods

fei li

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

mouseMethods-Backed
20130 equipment8 steps8 quotes
source-backed-method-package90/100

Hydrogen-Mediated Activation of the Nrf2/ HO -1 Signaling Pathway Improves Cognitive Impairment in Sleep-Deprived Mice methods

qifan xiao

Hydrogen-Mediated Activation of the Nrf2/ HO -1 Signaling Pathway Improves Cognitive Impairment in Sleep-Deprived Mice

mouseMethods-Backed
20260 equipment3 steps3 quotes
source-backed-method-package95/100

Gut Microbiota Composition in Male Rat Models under Different Nutritional Status and Physical Activity and Its Association with Serum Leptin and Ghrelin Levels methods

mar 237 a isabel queipo ortu 241 o

Gut Microbiota Composition in Male Rat Models under Different Nutritional Status and Physical Activity and Its Association with Serum Leptin and Ghrelin Levels

ratMethods-Backed
20130 equipment5 steps5 quotes
source-backed-method-package90/100

A Simple Auxin Transcriptional Response System Regulates Multiple Morphogenetic Processes in the Liverwort Marchantia polymorpha methods

eduardo flores sandoval

A Simple Auxin Transcriptional Response System Regulates Multiple Morphogenetic Processes in the Liverwort Marchantia polymorpha

Methods-Backed
20150 equipment8 steps8 quotes
source-backed-method-package90/100

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice methods

amanda atanasio

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice

mouseMethods-Backed
20160 equipment8 steps8 quotes
source-backed-method-package90/100

Association between depression during pregnancy and preterm birth: Results from population cohorts and mouse experimental models methods

siguo chen

Association between depression during pregnancy and preterm birth: Results from population cohorts and mouse experimental models

mouseMethods-Backed
20260 equipment8 steps8 quotes
source-backed-method-package90/100

Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance methods

yuki oe

Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance

mouseMethods-Backed
20200 equipment8 steps8 quotes