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replicatescience.com / protocols / evidence-backed methods

Protocol index

Browse reproducible experimental methods.

Step-by-step protocols from open-access papers, prioritized for methods evidence, equipment mapping, and canonical ConductGraph sync.

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323 experiments found

source-backed-method-package90/100

Synaptic changes contribute to persistent extra-motor behaviour deficits in amyotrophic lateral sclerosis methods

wei luan

Synaptic changes contribute to persistent extra-motor behaviour deficits in amyotrophic lateral sclerosis

mouseMethods-Backed
20250 equipment5 steps
PreviousPage 13 of 27Next
5 quotes
source-backed-method-package90/100

Wnt canonical pathway activator TWS119 drives microglial anti-inflammatory activation and facilitates neurological recovery following experimental stroke methods

degang song

Wnt canonical pathway activator TWS119 drives microglial anti-inflammatory activation and facilitates neurological recovery following experimental stroke

mouseMethods-Backed
20190 equipment7 steps7 quotes
source-backed-method-package95/100

Exposure of neonatal rats to alcohol has differential effects on neuroinflammation and neuronal survival in the cerebellum and hippocampus methods

lauren a topper

Exposure of neonatal rats to alcohol has differential effects on neuroinflammation and neuronal survival in the cerebellum and hippocampus

mouseMethods-Backed
20150 equipment3 steps3 quotes
source-backed-method-package90/100

RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury methods

andrea j mothe

RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury

mouseMethods-Backed
20170 equipment8 steps8 quotes
source-backed-method-package90/100

Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury methods

jessica l nielson

Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury

humanMethods-Backed
20150 equipment8 steps8 quotes
source-backed-method-package90/100

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability methods

erika assarsson

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

mouseMethods-Backed
20140 equipment8 steps8 quotes
source-backed-method-package90/100

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain methods

xiaobing yu

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

mouseMethods-Backed
20200 equipment8 steps8 quotes
source-backed-method-package95/100

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication methods

ozlem bozdagi

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

mouseMethods-Backed
20100 equipment8 steps8 quotes
source-backed-method-package95/100

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells methods

ke wang

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

humanMethods-Backed
20200 equipment8 steps8 quotes
source-backed-method-package90/100

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury methods

jie ren

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

ratMethods-Backed
20230 equipment8 steps8 quotes
source-backed-method-package90/100

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy methods

estelle woldt

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

mouseMethods-Backed
20130 equipment8 steps8 quotes
source-backed-method-package90/100

Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons methods

david dupret

Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons

Methods-Backed
20070 equipment8 steps8 quotes