FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis

Kodali M, Madhu LN, Kolla VSV, et al. Military Medical Research 2024;11(1):61.

The test records were read once by AI and checked by code. No person has reviewed them yet. How records are made

Open field test

Setting	Value	Paper’s words
Arena size	100 cm × 100 cm	“a brightly lit open field apparatus (100 cm × 100 cm Plexiglas open field box)”
Session duration	5 min	“Their movements were recorded using the Any-maze video tracking system for 5 min”
Illumination	brightly lit	“individually placed in the center of a brightly lit open field apparatus”
Other settings in the paper
Individually placed	in the center	“The rats from different groups were individually placed in the center of a brightly lit open field apparatus”
Open field box	Plexiglas	“100 cm × 100 cm Plexiglas open field box”
Neurobehavioral tasks	during the daytime	“animals in all groups were tested with a series of neurobehavioral tasks during the daytime”
Tested with a series of neurobehavioral tasks	Starting from the 11th week after VEH/CBD treatment	“Starting from the 11th week after VEH/CBD treatment, animals in all groups were tested with a series of neurobehavioral tasks”
Blinded	to group identification of animals or samples	“The investigators who performed the neurobehavioral tests, immunohistochemical or immunofluorescence quantifications, as well as biochemical assays remained blinded to group identification of animals or samples”
Apparatus
Any-maze video tracking system		“Their movements were recorded using the Any-maze video tracking system for 5 min”
Open field apparatus		“a brightly lit open field apparatus (100 cm × 100 cm Plexiglas open field box)”

Sucrose preference test

Compare with 4 other papers

Setting	Value	Paper’s words
Acclimatized to	Day 1 2 bottles	“the animal was acclimatized to 2 bottles on day 1”
Bottles	Day 1 sucrose-containing water (sweet water)	“2 bottles on day 1, each with sucrose-containing water (sweet water)”
Had access to	Day 2 sweet and standard water	“On day 2, the animal had access to sweet and standard water”
Food and water deprivation	Day 3 22 h	“On day 3, following a period of food and water deprivation lasting for 22 h”
Provided with access to	Day 3 sweet and standard water	“On day 3, following a period of food and water deprivation lasting for 22 h, the animal was once again provided with access to sweet and standard water”
Neurobehavioral tasks	during the daytime	“animals in all groups were tested with a series of neurobehavioral tasks during the daytime”
Tested with a series of neurobehavioral tasks	Starting from the 11th week after VEH/CBD treatment	“Starting from the 11th week after VEH/CBD treatment, animals in all groups were tested with a series of neurobehavioral tasks”
Blinded	to group identification of animals or samples	“The investigators who performed the neurobehavioral tests, immunohistochemical or immunofluorescence quantifications, as well as biochemical assays remained blinded to group identification of animals or samples”
Apparatus
Bottles		“the animal was acclimatized to 2 bottles on day 1”
Methods cited to other work
Detailed sucrose preference test methodology	our previous reports [30, 31]	“Detailed methodology regarding the SPT can be found in our previous reports [30, 31]”
Sucrose preference test as the measure of anhedonia	[58, 59]	“The degree of anhedonia, a depressive-like behavior, was evaluated through a sucrose preference test (SPT) [58, 59]”

FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis

Kodali M, Madhu LN, Kolla VSV, et al. Military Medical Research 2024;11(1):61.

The test records were read once by AI and checked by code. No person has reviewed them yet. How records are made

Open field test

Compare with 10 other papers

Setting	Value	Paper’s words
Arena size	100 cm × 100 cm	“a brightly lit open field apparatus (100 cm × 100 cm Plexiglas open field box)”
Session duration	5 min	“Their movements were recorded using the Any-maze video tracking system for 5 min”
Illumination	brightly lit	“individually placed in the center of a brightly lit open field apparatus”
Other settings in the paper
Individually placed	in the center	“The rats from different groups were individually placed in the center of a brightly lit open field apparatus”
Open field box	Plexiglas	“100 cm × 100 cm Plexiglas open field box”
Neurobehavioral tasks	during the daytime	“animals in all groups were tested with a series of neurobehavioral tasks during the daytime”
Tested with a series of neurobehavioral tasks	Starting from the 11th week after VEH/CBD treatment	“Starting from the 11th week after VEH/CBD treatment, animals in all groups were tested with a series of neurobehavioral tasks”
Blinded	to group identification of animals or samples	“The investigators who performed the neurobehavioral tests, immunohistochemical or immunofluorescence quantifications, as well as biochemical assays remained blinded to group identification of animals or samples”
Apparatus
Any-maze video tracking system		“Their movements were recorded using the Any-maze video tracking system for 5 min”
Open field apparatus		“a brightly lit open field apparatus (100 cm × 100 cm Plexiglas open field box)”

Sucrose preference test

Compare with 4 other papers

Setting	Value	Paper’s words
Acclimatized to	Day 1 2 bottles	“the animal was acclimatized to 2 bottles on day 1”
Bottles	Day 1 sucrose-containing water (sweet water)	“2 bottles on day 1, each with sucrose-containing water (sweet water)”
Had access to	Day 2 sweet and standard water	“On day 2, the animal had access to sweet and standard water”
Food and water deprivation	Day 3 22 h	“On day 3, following a period of food and water deprivation lasting for 22 h”
Provided with access to	Day 3 sweet and standard water	“On day 3, following a period of food and water deprivation lasting for 22 h, the animal was once again provided with access to sweet and standard water”
Neurobehavioral tasks	during the daytime	“animals in all groups were tested with a series of neurobehavioral tasks during the daytime”
Tested with a series of neurobehavioral tasks	Starting from the 11th week after VEH/CBD treatment	“Starting from the 11th week after VEH/CBD treatment, animals in all groups were tested with a series of neurobehavioral tasks”
Blinded	to group identification of animals or samples	“The investigators who performed the neurobehavioral tests, immunohistochemical or immunofluorescence quantifications, as well as biochemical assays remained blinded to group identification of animals or samples”
Apparatus
Bottles		“the animal was acclimatized to 2 bottles on day 1”
Methods cited to other work
Detailed sucrose preference test methodology	our previous reports [30, 31]	“Detailed methodology regarding the SPT can be found in our previous reports [30, 31]”
Sucrose preference test as the measure of anhedonia	[58, 59]	“The degree of anhedonia, a depressive-like behavior, was evaluated through a sucrose preference test (SPT) [58, 59]”