Source Paper
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair
Li Y, Hu J, Ran B, Zhong H, Zhong N et al.
Mater Today Bio • 2026
Accelerating Rotarod Test
Objective: Motor coordination and balance evaluation following spinal cord injury
This is a Accelerating Rotarod Test protocol using Mouse as the model organism. The procedure involves 3 procedural steps, 1 equipment items. Extracted from a 2026 paper published in Mater Today Bio.
Model and subjects
Mouse • C57BL/6 • Female • 8 weeks old • Not specified
Study window
Estimated timing pending
Core workflow
Pre-training phase • Post-SCI testing • Trial execution
Primary readouts
- Average latency to fall from rotarod
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Pre-training phase
Train mice for three consecutive days to establish stable baseline latencies before SCI
View evidence from paper
“Mice were pre-trained for three consecutive days to establish stable baseline latencies”
Post-SCI testing
After spinal cord injury, conduct rotarod testing with accelerating speed from 4-40 rpm over 300 seconds
View evidence from paper
“Motor coordination and balance were further evaluated using an accelerating rotarod (4–40 rpm over 300 s)”
Trial execution
Record average latency to fall over three trials per day with 15-minute intervals between trials
View evidence from paper
“After SCI, the average latency to fall was recorded over three trials per day, with 15-min intervals between trials”