Source Paper
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair
Li Y, Hu J, Ran B, Zhong H, Zhong N et al.
Mater Today Bio • 2026
Accelerating Rotarod Test
behavioralMouseC57BL/6
Objective: Motor coordination and balance evaluation following spinal cord injury
Materials & Equipment Checklist
1 item1 from ConductScience
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Equipment1
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Protocol Steps
1
Pre-training phase
Train mice for three consecutive days to establish stable baseline latencies before SCI
View evidence from paper
“Mice were pre-trained for three consecutive days to establish stable baseline latencies”
2
Post-SCI testing
After spinal cord injury, conduct rotarod testing with accelerating speed from 4-40 rpm over 300 seconds
View evidence from paper
“Motor coordination and balance were further evaluated using an accelerating rotarod (4–40 rpm over 300 s)”
3
Trial execution
Record average latency to fall over three trials per day with 15-minute intervals between trials
View evidence from paper
“After SCI, the average latency to fall was recorded over three trials per day, with 15-min intervals between trials”