Acoustic Startle Response Test
behavioralmouseparkin null mice (targeted deletion of parkin exon 7)
Objective: Assessment of norepinephrine-dependent startle response in parkin null mice to evaluate the role of locus coeruleus catecholaminergic neurons in acoustic startle
Materials & Equipment Checklist
1 item1 from ConductScience
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Equipment1
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Protocol Steps
1
Acoustic Startle Response Assessment
Mice were tested for acoustic startle response to evaluate norepinephrine-dependent startle function
Not specifiedNot specified
Note: The test specifically measures norepinephrine-dependent startle response, which is reduced in parkin null mice
View evidence from paper
“dramatic reduction of the norepinephrine-dependent startle response”