Amphetamine-Induced Hyperactivity Test
Objective: Measurement of increased susceptibility to amphetamine-induced hyperactivity in GSK3 knockin mice compared to wild-type controls
This is a Amphetamine-Induced Hyperactivity Test protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2010 paper published in Neuropsychopharmacology.
Model and subjects
mouse • GSK3 α/β 21A/21A/9A/9A knockin mice and wild-type controls • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Amphetamine-Induced Hyperactivity Test
Primary readouts
- Susceptibility to amphetamine-induced hyperactivity
- Behavioral response differences between GSK3 knockin and wild-type mice
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Amphetamine-Induced Hyperactivity Test
Behavioral measurement of hyperactivity response to amphetamine administration in GSK3 knockin mice versus wild-type controls
Note: GSK3 knockin mice displayed increased susceptibility to amphetamine-induced hyperactivity compared to controls
View evidence from paper
“GSK3 knockin mice displayed increased susceptibility to amphetamine-induced hyperactivity and to stress-induced depressive-like behaviors”