Attentional Set-Shifting Test
Objective: Assessed attentional set-shifting abilities in transgenic and mutant mice with different COMT expression levels
Protocol Steps
Attentional Set-Shifting Test
Assessed attentional set-shifting abilities in transgenic and mutant mice with different COMT expression levels
Note: Test was performed on Val-tg mice (overexpressing human COMT-Val polymorphism), COMT null mutation mice, and wild-type controls
View evidence from paper
“Increased COMT enzyme activity in Val-tg mice resulted in disrupted attentional set-shifting abilities”