Behavioral Testing
Objective: Assess phenotypic differences in awake mice through behavioral testing
This is a Behavioral Testing protocol using mouse as the model organism. The procedure involves 3 procedural steps. Extracted from a 2011 paper published in Molecular Psychiatry.
Model and subjects
mouse • PV-Cre/NR1f/f and littermate controls (NR1f/f) • male • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Animal generation and breeding • Subject selection for behavioral testing • Conduct behavioral tests
Primary readouts
- Phenotypic differences between PV-Cre/NR1f/f mice and littermate controls
Key equipment and reagents
Verified items
0
Direct vendor links
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Protocol Steps
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Animal generation and breeding
Generate PV-Cre/NR1f/f mice by crossing PV-Cre mice with mice carrying floxed NR1 alleles
Note: Littermate male controls (NR1f/f) were used for behavioral testing comparisons
View evidence from paper
“We generated PV-Cre/NR1f/f mice by crossing of PV-Cre mice with mice carrying 'floxed' NR1 alleles”
Subject selection for behavioral testing
Select male PV-Cre/NR1f/f mice and littermate male controls (NR1f/f) for awake behavioral tests
Note: Only male mice were used for awake electrophysiology and behavior tests
View evidence from paper
“In awake electrophysiology and behavior tests, male PV-Cre/NR1f/f mice and littermate male controls (NR1f/f) were used”
Conduct behavioral tests
Perform behavioral tests on awake mice to assess phenotypic differences between genotypes
Note: Specific behavioral tests are not detailed in the provided methods text
View evidence from paper
“In awake electrophysiology and behavior tests, male PV-Cre/NR1f/f mice and littermate male controls (NR1f/f) were used”