Chronic Social Defeat Stress
Objective: To assess food-reward behavior using conditioned place preference (CPP) task in mice after exposure to chronic social defeat stress (CSDS), a model of prolonged psychosocial stress
This is a Chronic Social Defeat Stress protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 equipment items. Extracted from a 2011 paper published in Journal of Clinical Investigation.
Model and subjects
mouse • Not specified in provided text • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Chronic Social Defeat Stress (CSDS) Exposure • Conditioned Place Preference (CPP) Task
Primary readouts
- CPP for high-fat diet
- Intake of high-fat diet
- Stress-induced food-reward behavior
- Ghrelin-dependent signaling effects
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Chronic Social Defeat Stress (CSDS) Exposure
Mice are exposed to chronic social defeat stress, a model of prolonged psychosocial stress featuring aspects of major depression and posttraumatic stress disorder
Note: CSDS is described as a model of prolonged psychosocial stress with characteristics relevant to major depression and PTSD
View evidence from paper
“exposure to chronic social defeat stress (CSDS), a model of prolonged psychosocial stress, featuring aspects of major depression and posttraumatic stress disorder”
Conditioned Place Preference (CPP) Task
Food-reward behavior is assessed using a CPP task in mice following CSDS exposure
Note: CPP task measures preference for environments associated with high-fat diet
View evidence from paper
“food-reward behavior, assessed using a conditioned place preference (CPP) task, is monitored in mice after exposure to chronic social defeat stress”