Conditioned Place Preference
Objective: Assessment of food-reward behavior by measuring preference for environments associated with high-fat diet consumption in mice exposed to chronic social defeat stress
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Protocol Steps
Chronic Social Defeat Stress (CSDS) Exposure
Mice are exposed to chronic social defeat stress, a model of prolonged psychosocial stress featuring aspects of major depression and posttraumatic stress disorder
Note: CSDS is the stressor condition prior to CPP testing
View evidence from paper
“exposure to chronic social defeat stress (CSDS), a model of prolonged psychosocial stress, featuring aspects of major depression and posttraumatic stress disorder”
Conditioned Place Preference Task
Food-reward behavior is assessed using a conditioned place preference task in mice after CSDS exposure
Conditioned Place Preference - Mouse (Custom Order)
Matches: Conditioned Place Preference (CPP) apparatus
Note: CPP measures preference for environments associated with high-fat diet consumption
View evidence from paper
“food-reward behavior, assessed using a conditioned place preference (CPP) task, is monitored in mice after exposure to chronic social defeat stress”
Measurement of High-Fat Diet Preference and Intake
Both CPP for and intake of high-fat diet are measured under the CSDS regime
Note: CSDS increased both CPP for and intake of high-fat diet
View evidence from paper
“Under this regime, CSDS increased both CPP for and intake of high-fat diet”