Contextual Fear Conditioning
behavioralmouseMecp2 308 mutant mice
Objective: Evaluation of contextual fear memory in Mecp2 mutant mice to assess hippocampus-dependent learning and memory function
Protocol Steps
1
Contextual Fear Conditioning Test
Mice were subjected to contextual fear conditioning to evaluate hippocampus-dependent contextual fear memory
Not specifiedNot specified
Note: This was one of three memory tasks performed; contextual fear memory was significantly impaired in Mecp2 308/Y mutant males
View evidence from paper
“Hippocampus-dependent spatial memory, contextual fear memory, and social memory were significantly impaired in Mecp2 308 mutant males”