Cued Fear Conditioning Test
behavioralmouseDcx mutant mice (hemizygous males and heterozygous females)
Objective: Assessment of cue-dependent fear learning and memory in Dcx mutant mice to evaluate hippocampal-dependent learning deficits
Protocol Steps
1
Cued Conditioned Fear Test
Behavioral test to assess cue-dependent fear learning and memory in Dcx mutant mice
Not specifiedNot specified
Note: Test was performed on both heterozygous females and hemizygous males; defects were observed in cued conditioned fear tests
View evidence from paper
“Behavioral tests show defects in context and cued conditioned fear tests, suggesting that deficits in hippocampal learning accompany the abnormal cytoarchitecture.”