Cylinder Test
Objective: Assessment of spontaneous activity in a cylinder to detect sensorimotor deficits and motor impairments in mice
This is a Cylinder Test protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 equipment items. Extracted from a 2004 paper published in Journal of Neuroscience.
Model and subjects
mouse • Wild-type and ASO (alpha-synuclein overexpressing) • male • Tested every 2 months for 8 months, starting at baseline
Study window
Estimated timing pending
Core workflow
Baseline and Longitudinal Testing Schedule • Cylinder Test Assessment
Primary readouts
- Spontaneous activity levels in cylinder
- Reduction in spontaneous activity as indicator of motor deficit
Key equipment and reagents
Verified items
0
Direct vendor links
0
Use this page as an execution guide, then fall back to the source paper whenever you need exact exclusions, dosing details, or assay-specific caveats.
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Protocol Steps
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Baseline and Longitudinal Testing Schedule
Male wild-type and ASO mice were tested for spontaneous activity in a cylinder as part of a battery of sensorimotor tests
Note: This test was part of a comprehensive sensorimotor assessment battery that also included challenging beam, inverted grid, pole, adhesive removal test, and gait analysis
View evidence from paper
“Male wild-type and ASO mice were tested every 2 months for 8 months for motor performance and coordination on a challenging beam, inverted grid, and pole, sensorimotor deficits in an adhesive removal test, spontaneous activity in a cylinder, and gait”
Cylinder Test Assessment
Assess spontaneous activity of mice in the cylinder apparatus
Note: Sensitive to alterations in the nigrostriatal dopaminergic system
View evidence from paper
“examined the motor deficits in ASO mice with a battery of sensorimotor tests that are sensitive to alterations in the nigrostriatal dopaminergic system”