Cylinder Test
behavioralmouseWild-type and ASO (alpha-synuclein overexpressing)
Objective: Assessment of spontaneous activity in a cylinder to detect sensorimotor deficits and motor impairments in mice
Materials & Equipment Checklist
1 item
Gather these items before starting the experiment. Check off items as you prepare.
Equipment1
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Protocol Steps
1
Baseline and Longitudinal Testing Schedule
Male wild-type and ASO mice were tested for spontaneous activity in a cylinder as part of a battery of sensorimotor tests
Testing conducted every 2 months for 8 months total
Note: This test was part of a comprehensive sensorimotor assessment battery that also included challenging beam, inverted grid, pole, adhesive removal test, and gait analysis
View evidence from paper
“Male wild-type and ASO mice were tested every 2 months for 8 months for motor performance and coordination on a challenging beam, inverted grid, and pole, sensorimotor deficits in an adhesive removal test, spontaneous activity in a cylinder, and gait”
2
Cylinder Test Assessment
Assess spontaneous activity of mice in the cylinder apparatus
Note: Sensitive to alterations in the nigrostriatal dopaminergic system
View evidence from paper
“examined the motor deficits in ASO mice with a battery of sensorimotor tests that are sensitive to alterations in the nigrostriatal dopaminergic system”