Protocol Steps

Animal treatment initiation

Male v-WT and v-TK transgenic mice begin valganciclovir treatment at 8 weeks of age

12 weeks for behavioral testing cohortNot specified

Note: Different treatment durations for different experiments (8 weeks for dexamethasone, 10-19 weeks for endocrine, 12 weeks for behavior, 4 weeks for histology)

View evidence from paper

“Male v-WT and v-TK mice were treated with valganciclovir for 8 weeks (dexamethasone experiment), 10-19 weeks (endocrine), 12 weeks (behavior) or 4 weeks (histology), beginning at 8 weeks of age”

Behavioral testing preparation

Mice undergo 30 minutes of restraint or are tested directly from home cage prior to behavioral testing

30 minutes restraintNot specified

Note: Different cohorts tested in different behavioral tests

View evidence from paper

“Behavioral tests were performed following 30 min of restraint or directly from the home cage”