Source Paper
Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP
You-Ming Lu, Zhengping Jia, Christopher Janus, Jeffrey T. Henderson, Robert Gerlai et al.
Journal of Neuroscience • 1997
Fear Conditioning Test
behavioralmousemGluR5 mutant mice
Objective: Assessment of contextual information acquisition and memory in mGluR5 mutant mice using fear conditioning
Protocol Steps
1
Fear Conditioning Test
Mice were tested for contextual information acquisition and memory using a fear-conditioning test
Not specifiedNot specified
Note: The test was used to assess whether mGluR5 mutant mice were impaired in the acquisition and use of contextual information
View evidence from paper
“These mutant mice were also impaired in the acquisition and use of spatial information in both the Morris water maze and contextual information in the fear-conditioning test.”