Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors

Estefanía P Bello, Yolanda Mateo, Diego M Gelman, Daniela Noaín, Jung H Shin et al.

Nature Neuroscience • 2011

DOI PMC

Food-Seeking Motivation Assay

behavioralmouseautoDrd2KO (Drd2 loxP/loxP; Dat +/IRES-cre)

Objective: Measurement of motivation for food reward in autoDrd2KO mice lacking dopamine D2 autoreceptors

Protocol Steps

Food-Seeking Motivation Assessment

Measurement of enhanced motivation for food reward in autoDrd2KO mice

Not specifiedNot specified

Note: The methods section provided does not contain detailed procedural steps for the food-seeking motivation assay. Only the abstract and introduction are included in the extracted text.

View evidence from paper

“The mice also exhibited increased place preference for cocaine and enhanced motivation for food reward.”