Role of the Dorsal Medial Habenula in the Regulation of Voluntary Activity, Motor Function, Hedonic State, and Primary Reinforcement

Yun-Wei A. Hsu, Si D. Wang, Shirong Wang, Glenn Morton, Hatim A. Zariwala et al.

Journal of Neuroscience • 2014

Forced Swim Test

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Objective: Measurement of depression-related behaviors in mice with dorsal medial habenula lesions using the forced swim test

Materials & Equipment Checklist

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Forced swim test apparatus

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Mice were subjected to the forced swim test as a measure of depression-related behavior

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Forced Swim Test Apparatus

Note: This test was used to assess depression-related phenotypes in mice with dMHb lesions

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“show deficits in sucrose preference, but not in the forced swim test, two measures of depression-related phenotypes in rodents”