Gait and Motor Function Testing
Objective: Analysis of gait and motor dysfunctions in Adnp+/- mice and evaluation of NAP treatment efficacy on motor function
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Materials1
Coronis Neurosciences • CP201 • Not specified • Not specified
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Protocol Steps
Gait and Motor Function Assessment
Evaluation of gait and motor dysfunctions in Adnp+/- mice
Note: Specific testing apparatus and methodology not detailed in provided text
View evidence from paper
“Adnp+/- mice further exhibited global developmental delays, vocalization impediments, gait and motor dysfunctions”
NAP Treatment Administration
Daily NAP administration via systemic or nasal routes
Note: Treatment was administered both systemically and nasally
View evidence from paper
“all of which were partially reversed by daily NAP administration (systemic/nasal)”
Post-Treatment Motor Function Evaluation
Re-assessment of gait and motor function following NAP treatment
Note: Motor dysfunctions were partially reversed by NAP treatment
View evidence from paper
“gait and motor dysfunctions, and social and object memory impairments, all of which were partially reversed by daily NAP administration”