Gastric Emptying Measurement
Objective: Measurement of the rate of gastric emptying after administration of GHS-R antagonists in mice
This is a Gastric Emptying Measurement protocol using mouse as the model organism. The procedure involves 2 procedural steps, 2 materials. Extracted from a 2003 paper published in Gut.
Model and subjects
mouse • ob/ob obese mice and lean mice with diet-induced obesity • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Administer GHS-R antagonist • Measure gastric emptying
Primary readouts
- Rate of gastric emptying
- Energy intake
- Body weight gain
- Glycaemic control
Key equipment and reagents
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Protocol Steps
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Administer GHS-R antagonist
Administer GHS-R antagonist to experimental animals
Note: Repeated administration protocol used for ob/ob obese mice
View evidence from paper
“Repeated administration of GHS-R antagonist was continued for six days in ob/ob obese mice”
Measure gastric emptying
Measure the rate of gastric emptying following GHS-R antagonist administration
Note: Measurement methodology not detailed in provided text
View evidence from paper
“Energy intake and gastric emptying were measured after administration of GHS-R antagonists”