Source Paper
High‐mobility Group Protein 1/ Receptor for Advanced Glycation End Products/ Nuclear Factor‐κB Signalling Pathway Contributes to the Pathogenic Process of Striatal Neuron Impairment in the Rat Model of Parkinson's Disease
Zhu Y, Du Z, Sun L, Huang Z, Jia L et al.
Brain Behav • 2026
Grip Strength Test
behavioralSprague-Dawley ratsSD
Objective: To evaluate grip strength by measuring the duration rats can hang onto a wire
Protocol Steps
1
Test timing
Conduct the grip strength test 4 weeks after surgery
View evidence from paper
“We conducted the GST following the established procedures, 4 weeks post‐surgery”
2
Wire setup
Suspend a wire with specific dimensions at a defined height
View evidence from paper
“suspended a wire with a diameter of 2 mm and a length of 35 cm, positioned 50 cm above the ground”
3
Measurement procedure
Time how long rats can hang onto the wire to assess grip strength
View evidence from paper
“timed the duration for which the rats hung onto the wire to evaluate their grip strength”
4
Test schedule
Perform the test three times daily for 5 consecutive days
View evidence from paper
“The test was carried out three times a day for a total of 5 days of testing”
5
Blinding
Keep observers blinded to experimental conditions
View evidence from paper
“The experimental conditions for the rats were kept concealed from the observers”