Grooming Behavior Assessment
Objective: Measurement of repetitive self-grooming behavior as an indicator of stereotypy in Shank3 null mutant mice
This is a Grooming Behavior Assessment protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2012 paper published in Journal of Neuroscience.
Model and subjects
mouse • Shank3 null mutant and heterozygous mice • unknown • adolescent and adult • not specified in provided text
Study window
Estimated timing pending
Core workflow
Grooming Behavior Assessment
Primary readouts
- Frequency of repetitive self-grooming behavior
- Presence or absence of stereotypic grooming patterns
Key equipment and reagents
Verified items
0
Direct vendor links
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Protocol Steps
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Grooming Behavior Assessment
Repetitive self-grooming behavior was measured as an indicator of stereotypy in Shank3 mutant mice
Note: Repetitive self-grooming was detected only in some cohorts, emphasizing importance of replication analyses
View evidence from paper
“Repetitive self-grooming, reduced ultrasonic vocalizations, and deficits in reversal of water maze learning were detected only in some cohorts”