High-Fat Diet Intake Measurement
Objective: Quantification of high-fat diet consumption in mice under chronic social defeat stress conditions, assessing stress-induced food-reward behavior
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Protocol Steps
Chronic Social Defeat Stress (CSDS) Exposure
Mice are exposed to chronic social defeat stress, a model of prolonged psychosocial stress featuring aspects of major depression and posttraumatic stress disorder
Note: CSDS is the stressor condition under which food-reward behavior is subsequently measured
View evidence from paper
“exposure to chronic social defeat stress (CSDS), a model of prolonged psychosocial stress, featuring aspects of major depression and posttraumatic stress disorder”
Conditioned Place Preference Task
Food-reward behavior is assessed using a CPP task in mice following CSDS exposure
Conditioned Place Preference - Mouse (Custom Order)
Matches: Conditioned Place Preference (CPP) apparatus
Note: CPP measures preference for environments associated with high-fat diet consumption
View evidence from paper
“food-reward behavior, assessed using a conditioned place preference (CPP) task, is monitored in mice after exposure to chronic social defeat stress”
High-Fat Diet Intake Measurement
Quantification of high-fat diet consumption is measured in stressed mice
Note: CSDS increased both CPP for and intake of high-fat diet
View evidence from paper
“CSDS increased both CPP for and intake of high-fat diet, and stress-induced food-reward behavior was dependent on signaling by the peptide hormone ghrelin”