Hindlimb Clasping Phenotype Assessment
Objective: Observation and characterization of hindlimb clasping behavior in adult Emx-BDNF KO mice to assess phenotypic manifestations similar to Huntington's disease models
This is a Hindlimb Clasping Phenotype Assessment protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2004 paper published in Journal of Neuroscience.
Model and subjects
mouse • Emx-BDNF KO mice • unknown • Adult (specific ages mentioned: 35 days, 120 days, and beyond 1 year) • Not specified
Study window
Estimated timing pending
Core workflow
Hindlimb Clasping Phenotype Assessment
Primary readouts
- Presence and severity of hindlimb clasping behavior
- Comparison of phenotype to Huntington's disease mouse models
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Hindlimb Clasping Phenotype Assessment
Adult Emx-BDNF KO mice were observed for hindlimb clasping behavior, a phenotype similar to that observed in mouse models of Huntington's disease
Note: This is a behavioral observation task assessing motor phenotype
View evidence from paper
“Adult Emx-BDNF KO mice display a hindlimb clasping phenotype similar to that observed in mouse models of Huntington's disease”