Immediate Memory Task
behavioralmouseNot specified in provided text
Objective: Assessment of immediate memory function in mice with SIRT1 deficiency and overexpression to evaluate the role of SIRT1 in cognitive abilities
Protocol Steps
1
Behavioral Assessment of Immediate Memory
Conducted behavioral paradigms to analyze effects of SIRT1 deficiency and overexpression on mouse immediate memory function
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Note: Part of combination of behavioral and electrophysiological paradigms used to assess cognitive function
View evidence from paper
“Using a combination of behavioral and electrophysiological paradigms, we analyzed the effects of SIRT1 deficiency and overexpression on mouse learning and memory”
2
Evaluation of Cognitive Deficits
Demonstrated that absence of SIRT1 impaired cognitive abilities including immediate memory, classical conditioning, and spatial learning
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Note: Specific behavioral tests used for immediate memory assessment not detailed in provided text
View evidence from paper
“We demonstrated that the absence of SIRT1 impaired cognitive abilities, including immediate memory, classical conditioning, and spatial learning”