Inverted Grid Test
Objective: Assessment of motor performance and coordination on an inverted grid as part of a sensorimotor test battery sensitive to nigrostriatal dopaminergic system alterations
This is a Inverted Grid Test protocol using mouse as the model organism. The procedure involves 2 procedural steps, 1 equipment items. Extracted from a 2004 paper published in Journal of Neuroscience.
Model and subjects
mouse • Wild-type and ASO (alpha-synuclein overexpressing) • male • Tested every 2 months for 8 months
Study window
Estimated timing pending
Core workflow
Testing Schedule • Inverted Grid Assessment
Primary readouts
- Motor performance on inverted grid
- Coordination on inverted grid
- Grip strength and balance maintenance
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Testing Schedule
Male wild-type and ASO mice were tested for motor performance and coordination on the inverted grid as part of a battery of sensorimotor tests
Note: Testing was conducted at regular 2-month intervals over an 8-month period
View evidence from paper
“Male wild-type and ASO mice were tested every 2 months for 8 months for motor performance and coordination on a challenging beam, inverted grid, and pole”
Inverted Grid Assessment
Mice were assessed on the inverted grid to measure motor performance and coordination as part of the sensorimotor test battery
Note: This test is sensitive to alterations in the nigrostriatal dopaminergic system
View evidence from paper
“examined the motor deficits in ASO mice with a battery of sensorimotor tests that are sensitive to alterations in the nigrostriatal dopaminergic system”