Source Paper
Hyperactivity and Intact Hippocampus-Dependent Learning in Mice Lacking the M<sub>1</sub>Muscarinic Acetylcholine Receptor
Tsuyoshi Miyakawa, Masahisa Yamada, Alokesh Duttaroy, Jürgen Wess
Journal of Neuroscience • 2001
Light/Dark Transition Test
Objective: Assessment of anxiety-like behavior based on preference for light versus dark compartments
This is a Light/Dark Transition Test protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2001 paper published in Journal of Neuroscience.
Model and subjects
mouse • Not specified in provided text • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Light/Dark Transition Test
Primary readouts
- Locomotor activity in light/dark transition test
- Preference for light versus dark compartments
- Anxiety-like behavior
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Light/Dark Transition Test
Mice were subjected to the light/dark transition test as part of a battery of behavioral tests to assess anxiety-like behavior and locomotor activity
Note: This test measures preference for light versus dark compartments as an indicator of anxiety-like behavior
View evidence from paper
“M1R−/− mice consistently exhibited a pronounced increase in locomotor activity in various tests, including open field, elevated plus maze, and light/dark transition tests”