Source Paper
Essential role of brain-derived neurotrophic factor in adult hippocampal function
Lisa M. Monteggia, Michel Barrot, Craig M. Powell, Olivier Berton, Victor Galanis et al.
Proceedings of the National Academy of Sciences • 2004
Locomotor Activity Assay
Objective: Measurement of hyperactivity phenotype in mice with developmental loss of forebrain BDNF
This is a Locomotor Activity Assay protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2004 paper published in Proceedings of the National Academy of Sciences.
Model and subjects
mouse • Not specified in provided text • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Locomotor Activity Assessment
Primary readouts
- Hyperactivity phenotype measurement
- Locomotor activity levels in mice with developmental BDNF loss
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Locomotor Activity Assessment
Measurement of hyperactivity phenotype in mice with developmental loss of forebrain BDNF using locomotor activity assay
Note: The text indicates that loss of BDNF during earlier stages of development causes hyperactivity, which was measured through this assay
View evidence from paper
“the loss of BDNF during earlier stages of development causes hyperactivity”