Source Paper
Essential role of brain-derived neurotrophic factor in adult hippocampal function
Lisa M. Monteggia, Michel Barrot, Craig M. Powell, Olivier Berton, Victor Galanis et al.
Proceedings of the National Academy of Sciences • 2004
Locomotor Activity Assay
Objective: Measurement of hyperactivity phenotype in mice with developmental loss of forebrain BDNF
Protocol Steps
Locomotor Activity Assessment
Measurement of hyperactivity phenotype in mice with developmental loss of forebrain BDNF using locomotor activity assay
Note: The text indicates that loss of BDNF during earlier stages of development causes hyperactivity, which was measured through this assay
View evidence from paper
“the loss of BDNF during earlier stages of development causes hyperactivity”