Locomotor Activity Testing
Objective: Measurement of spontaneous locomotor activity to assess hyperlocomotion in autoDrd2KO mice lacking dopamine D2 autoreceptors
This is a Locomotor Activity Testing protocol using mouse as the model organism. The procedure involves 1 procedural steps. Extracted from a 2011 paper published in Nature Neuroscience.
Model and subjects
mouse • autoDrd2KO (Drd2 loxP/loxP; Dat +/IRES-cre) • unknown • Not specified • Not specified
Study window
Estimated timing pending
Core workflow
Locomotor Activity Assessment
Primary readouts
- Spontaneous locomotor activity levels
- Hyperlocomotion phenotype in autoDrd2KO mice
- Comparison of motor activity between autoDrd2KO and control mice
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Locomotor Activity Assessment
Measurement of spontaneous locomotor activity in autoDrd2KO mice to assess hyperlocomotion phenotype
Note: Specific apparatus details, testing duration, and environmental conditions are not provided in the extracted text
View evidence from paper
“AutoDrd2KO mice displayed elevated DA synthesis and release, hyperlocomotion and supersensitivity to the psychomotor effects of cocaine”