Methamphetamine Response Testing
Objective: Measurement of locomotor response to methamphetamine administration in mice to assess differences in motor activity between genotypes
Protocol Steps
Methamphetamine Administration and Locomotor Response Testing
Mice were administered methamphetamine and their locomotor response was measured
Note: The experiment measured increased locomotor response to methamphetamine in heterozygous α3 and α1 isoform mice compared to controls
View evidence from paper
“increased locomotor response to methamphetamine, and a 40% reduction in hippocampal NMDA receptor expression”