Morris Water Maze
Objective: Assessed cognitive function and spatial learning deficits in transgenic mouse models of Alzheimer's disease
This is a Morris Water Maze protocol using mouse as the model organism. The procedure involves 1 procedural steps, 1 equipment items. Extracted from a 2011 paper published in Journal of Neuroscience.
Model and subjects
mouse • transgenic hAPP mice (human amyloid precursor protein overexpressing) • unknown • Not specified in provided text • Not specified in provided text
Study window
Estimated timing pending
Core workflow
Morris Water Maze Testing
Primary readouts
- Cognitive function assessment
- Spatial learning performance
- Cognitive decline in transgenic models
Key equipment and reagents
Verified items
0
Direct vendor links
0
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Protocol Steps
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Morris Water Maze Testing
Cognitive function and spatial learning assessment was performed on transgenic mouse models to evaluate deficits
Note: Testing was conducted on hAPP transgenic mice with varying tau and Fyn levels to assess cognitive decline
View evidence from paper
“Tau reduction prevented cognitive decline induced by synergistic effects of A and Fyn”