Morris Water Maze
behavioralmousetransgenic hAPP mice (human amyloid precursor protein overexpressing)
Objective: Assessed cognitive function and spatial learning deficits in transgenic mouse models of Alzheimer's disease
Materials & Equipment Checklist
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Equipment1
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Protocol Steps
1
Morris Water Maze Testing
Cognitive function and spatial learning assessment was performed on transgenic mouse models to evaluate deficits
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Note: Testing was conducted on hAPP transgenic mice with varying tau and Fyn levels to assess cognitive decline
View evidence from paper
“Tau reduction prevented cognitive decline induced by synergistic effects of A and Fyn”